Automated gesture tracking in head-fixed mice

Automated gesture tracking in head-fixed mice

BACKGROUND The preparation consisting of a head-fixed mouse on a spherical or cylindrical treadmill offers unique advantages in a variety of experimental contexts. Head fixation provides the mechanical stability necessary for optical and electrophysiological recordings and stimulation. Additionally, it can be combined with virtual environments such as T-mazes, enabling these types of recording ...

Automated Tracking of Whiskers in Videos of Head Fixed Rodents

We have developed software for fully automated tracking of vibrissae (whiskers) in high-speed videos (>500 Hz) of head-fixed, behaving rodents trimmed to a single row of whiskers. Performance was assessed against a manually curated dataset consisting of 1.32 million video frames comprising 4.5 million whisker traces. The current implementation detects whiskers with a recall of 99.998% and ident...

Vibrissa-based object localization in head-fixed mice.

Linking activity in specific cell types with perception, cognition, and action, requires quantitative behavioral experiments in genetic model systems such as the mouse. In head-fixed primates, the combination of precise stimulus control, monitoring of motor output, and physiological recordings over large numbers of trials are the foundation on which many conceptually rich and quantitative studi...

Vibrotactile Whisker Frequency Discrimination in Head-Fixed Mice

A Novel Two-alternative Forced Choice Paradigm for Bilateral 3 Vibrotactile Whisker Frequency Discrimination in Head-Fixed Mice 4 and Rats 5 Johannes M. Mayrhofer, Vida Skreb, Wolfger von der Behrens, Simon Musall, Bruno Weber and 6 Florent Haiss* 7 8 Institute of Pharmacology and Toxicology, University of Zürich, Zürich, Switzerland 9 10 Running title: bilateral frequency discrimination in hea...

Correction: Procedures for Behavioral Experiments in Head-Fixed Mice